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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPCN2
All Species:
9.39
Human Site:
T253
Identified Species:
20.67
UniProt:
Q8NHX9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHX9
NP_620714.2
752
85243
T253
G
Q
D
R
E
R
L
T
Y
F
Q
N
L
P
E
Chimpanzee
Pan troglodytes
XP_001173935
763
85554
F262
D
R
E
R
L
T
Y
F
Q
N
L
P
E
S
L
Rhesus Macaque
Macaca mulatta
XP_001101571
752
85154
T253
G
Q
D
R
E
R
R
T
Y
F
Q
N
L
P
E
Dog
Lupus familis
XP_540804
876
99392
I378
G
Q
D
R
E
R
L
I
Y
F
R
N
L
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWC0
731
83577
A237
A
Q
D
Q
E
R
L
A
Y
F
R
N
L
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506335
738
85478
E240
R
Q
D
Q
E
R
L
E
Y
F
R
N
L
P
D
Chicken
Gallus gallus
NP_001137403
752
87078
P226
L
V
T
T
A
N
S
P
D
V
M
M
P
A
F
Frog
Xenopus laevis
NP_001089672
327
37780
Zebra Danio
Brachydanio rerio
A0JMD4
774
89166
T266
K
Q
N
G
E
W
Q
T
Y
F
R
N
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138448
798
92257
Q301
R
I
F
Q
E
G
M
Q
H
F
A
S
I
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KI8
733
84855
T246
E
D
T
Q
Q
G
L
T
V
F
T
S
Y
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
95.3
71.1
N.A.
72.8
N.A.
N.A.
69.5
28.1
29.2
54.6
N.A.
N.A.
N.A.
N.A.
42.4
Protein Similarity:
100
92.4
96.9
77
N.A.
84.7
N.A.
N.A.
82.3
48.9
36.2
72.2
N.A.
N.A.
N.A.
N.A.
60.4
P-Site Identity:
100
6.6
93.3
86.6
N.A.
73.3
N.A.
N.A.
66.6
0
0
53.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
20
93.3
93.3
N.A.
86.6
N.A.
N.A.
86.6
0
0
73.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
10
0
0
10
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
46
0
0
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
10
0
10
0
64
0
0
10
0
0
0
0
10
0
46
% E
% Phe:
0
0
10
0
0
0
0
10
0
73
0
0
0
0
10
% F
% Gly:
28
0
0
10
0
19
0
0
0
0
0
0
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
0
0
0
10
0
46
0
0
0
10
0
55
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
10
0
55
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
10
10
55
0
% P
% Gln:
0
55
0
37
10
0
10
10
10
0
19
0
0
0
0
% Q
% Arg:
19
10
0
37
0
46
10
0
0
0
37
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
19
0
10
0
% S
% Thr:
0
0
19
10
0
10
0
37
0
0
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
55
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _